Caesalpinia bonducella L. In the present study, attempts were made to assess the physicochemical, phytochemical, nutritional and pharmacological properties of C. Powder microscopy revealed characteristics features of C. Physicochemical properties such as foreign matter 0. Phytochemical analysis revealed the presence of alkaloid 0.
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Caesalpinia bonducella L. In the present study, attempts were made to assess the physicochemical, phytochemical, nutritional and pharmacological properties of C. Powder microscopy revealed characteristics features of C. Physicochemical properties such as foreign matter 0.
Phytochemical analysis revealed the presence of alkaloid 0. The nutritional profile of C. Presence of different phytochemicals was confirmed in the hexane and chloroform extracts of C. Thus the present investigation provides scientific evidence for the folk-lore claims for medicinal value of C.
Peoples of all ages in both developing and undeveloped countries use plants in an attempt to cure various diseases and to get relief from physical sufferings.
For centuries, plant and plant products have been used for treating various illnesses. Current researchers primarily focused on plants, since they can be sourced easily and selection is mostly based on their ethno-medicinal claims Chaudhari et al. Usage of plant materials in preventing and treating inflammatory, oxidative stress and microbial mediated diseases over the past few years has attracted the attention of scientists worldwide Seth and Sharma, Today, several medicinal plant s and their products are still being employed as home remedies, over the counter drugs as well as raw materials for the pharmaceutical industry and they represent a substantial proportion of the global drug market.
However, a key obstacle, which has hindered the acceptance of the alternative medicines in the developed countries is the lack of documentation and stringent quality control. There is a need for documentation of research work that has to be carried out on traditional medicines.
Therefore, it has become extremely important to make an effort towards standardization of the plant material to be used as medicine as well as nutraceutical Kumar et al. Nutraceuticals can play an important role in preventing these diseases and increasing healthy society. In this connection, the present work was attempted to evaluate the nutraceutical properties of aqueous extracts of seeds of Caesalpinia bonducella L.
Family, Caesalpiniaceae , a common Indian folk-lore drug. The seeds of C. In and around Chennai, an ointment is made from the C. The seeds are considered as tonic, febrifuge, anthelmintic and anti-blennorrhagic Nazeerullah et al. The oil from the seeds is used in convulsions and paralysis Moon et al. The antimicrobial activity of ethanolic extract of C.
Even though some traditional uses and medicinal properties of C. Hence, the purpose of the present study was to evaluate the phyto chemical properties , chemical composition , nutritional value and medicinal properties such as anti-inflammatory and antioxidant activities of C. Sample collection: The seeds of Caesalpinia bonducella L.
Identification and authentication of seeds were carried out by Dr. The collected materials were cleaned, shade dried and coarsely powdered and used for further studies.
Physico chemical properties : Powder microscopic characteristics were observed under light microscope. The sensory nature and physico chemical properties of dry powder of selected plants will be analyzed according to IMHF Different chemical tests including fluorescence analysis were performed to qualitatively and quantitatively to identify the major chemical constituents Trease and Evans, ; Harborne, ; Edeoga et al.
Biochemical profile such as carbohydrate Southgate, , free amino acid Chen et al. X-ray fluorescence spectrophotometer, flame photometry, atomic absorption spectroscopy were used to analyze the mineral composition while, the phytochemical profile was evaluated by GC-MS and HPTLC techniques. Pharmacological properties: Aqueous extract of seeds of C. Then, the content was filtered through Whatman filter paper No. The anti-inflammatory activity was investigated based on in vitro methods such as inhibition of protein Albumin denaturation activity Alhakmani et al.
Similarly, antioxidant activity was determined using DPPH free radical scavenging assay Alhakmani et al. In this study, BHT is used as positive control. Physico chemical properties : The powder microscopy of C. Starch grains are simple and compound with round, oval, polygonal and irregular shaped margins with closely striated and central linear hilum.
Fatty oil globules and piriform fibres are also seen. The data obtained on sensory evaluation revealed that the selected part of C. Loss on drying is 8. Ash content 3. Solubility in water The extractive value suggests that the sample satisfies purity standards and is also rich in high polar compounds.
Among the different solvents, water extract of C. Preliminary phyto chemical analysis on water, hexane, ethanol, chloroform and ethyl acetate extract of C. Lignin recorded higher percentage of yield Secondary metabolites play both a defensive role against herbivore, pathogen attack and inter-plant competition and an attractant role towards beneficial organisms such as pollinators or symbionts Wink and Schimmer, Plant secondary products also have protective actions in relation to abiotic stresses such as those associated with changes in temperature, water status, light levels, UV exposure and mineral nutrients.
Furthermore, recent study has indicated potential role of secondary products at the cellular level as plant growth regulators, modulators of gene expression and in signal transduction Kaufman et al.
Phenolic compounds are one of the largest and most ubiquitous groups of plant metabolites Singh et al. Natural antioxidants mainly come from plants in the form of phenolic compounds such as flavonoids, phenolic acids , etc.
Ali et al. A number of studies have focused on the biological activities of phenolic compounds , which are potential antioxidants and free radical scavengers Singh, Flavonoids present in the plant might be responsible for anti-inflammatory properties Kunle and Egharevba, Tannins help in wound healing and as an anti-parasite and could reduce the risk of coronary heart disease s. Alkaloids are a diverse group of secondary metabolites found to exhibit antimicrobial activity.
Alkaloids are also known for decreasing blood pressure , balancing the nervous system in case of mental illness and also possess anti-malarial properties Batista et al. Fluorescence is an important phenomenon exhibited by various chemical constituents present in plant material. The seed powder as such and after treatment with various solvents was subjected to fluorescence analysis Table 4. Observations were made under visible light and under UV light of short wavelength and long wavelength separately.
Many phytochemicals fluorescence fluoresce when suitably illuminated. The fluorescence colour is specific for each compound. A non-fluorescent compound may fluorescence, if mixed with impurities that are fluorescent.
Hence, it is useful in detecting the adulterants and substituent. Some constituents show fluorescence in the visible range in many natural products e. If the substances themselves are not fluorescent, they may often be converted into fluorescent derivatives by applying different reagents hence, some crude drugs are often assessed qualitatively in this way and it is an important parameter of pharmacology evaluation Ali, Nutritional value: Nutritional value of C.
Energy value Intake of dietary fibres can lower the serum cholesterol level, risk of coronary heart disease , hypertension, constipation, diabetes, colon and breast cancer Ishida et al. Thus C. Other nutritional constituents found are total fat 3. Free fatty acid content is present as little as 0. In addition to this, the plant is rich in vitamins such as vitamin E 6. From this data, it can be deduced that seeds of C. Deficiency of calcium and phosphorous leads to the classical bone symptoms associated with rickets, such as bowlegs, knock knees, curvature of the spine and pelvic and thoracic deformities.
Fe could be used in the treatment of anemia. Magnesium plays important role in the structure and the function of the human body. Iron, zinc, copper and manganese are playing an important role in the improvement of antioxidant system.
The positive impact of zinc supplementation on the growth of some stunted children and on the prevalence of selected childhood diseases such as diarrhoea, suggests that zinc deficiency is likely to be a significant public health problem, especially in developing countries Osendarp et al.
Enzymes such as lipase Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide thereby, it prevent oxidative stress. A study from the Institute of Cytology and Genetics found that oxidative stress , accumulation of protein and DNA damage could be reduced in the presence of antioxidant enzymes catalase in the cytosol and mitochondrial extracts from liver cells of rats Sinitsyna et al.
This study also found that dietary supplements for increasing the activity of catalase in the liver mitochondria in rats led to reduced mitochondrial dysfunction and slowed the process of aging in these animals. One of the most familiar functions of lipase in the body is digestion of dietary fat. Another important function of lipases is to help the body package cholesterol for transport and also helps the biosynthesize the vitamins A, D, E and K.
The ALP hydrolyzes the phosphate moiety and makes tyrosine available for conversion to catecholamines that are then used to cross-link proteins during sclerotization Lunan and Mitchell, Phytochemical profile: In the last two decades High Performance Thin Layer Chromatography HPTLC method has emerged as an important tool for the qualitative and quantitative phyto chemical analysis of herbal drugs and formulation.
This includes TLC fingerprint profile and estimation of chemical markers. The HPTLC fingerprinting of the plant was presented with Rf values under and nm that confirm the presence of different type of phytochemical compounds in the aqueous extract of seeds of C. Five bands with blue Rf 0. Presence of such bands with different colour and Rf value indicated the occurrence of different types of phytochemicals in the extract of C.
The chloroform extract exhibited 11 major compounds like octane, hexanal, 2-heptenal z -, hexanoic acid, 2-decenal, e -, 2,4-decadienal, 2,4-decadienal, E, E -, benzene, 1-pentylheptyl -, 3,7,11,tetramethylhexadecenol, n-hexadecanoic acid and 9,octadecadienoic acid z,z Fig. Anti-inflammatory activity: Inflammation is a complex process, very often associated with pain. Anti-inflammatory compounds can act on various levels of patho-physiological process by blocking the biosynthesis of pro-inflammatory mediators, by decreasing the enzyme expression or by reducing substrate levels or by inhibiting the release of performed stored mediators, by blocking mediator-receptor interaction on target cells and immune stimulation, which results in less aggressive response to allergen challenge Mujumdar et al.
Inflammation is described as the succession of changes in a living tissue, when it is injured provided that the injury is not of such a degree as to at once destroy its structure and vitality, as well injure living microcirculation and related tissues Sanderson,
Caesalpinia bonducella F. - An Overview
Metrics details. Caesalpinia bonducella is an important medicinal plant for its traditional uses against different types of diseases. Therefore, the present study investigated the antimicrobial, antidiarrhoeal, and cytotoxic activities of the methanol extract and ethyl acetate, chloroform, and petroleum ether pet. The antibacterial potentialities of methanol extract and its fractions of C. The fractions were subjected to a brine shrimp lethality test to evaluate their cytotoxicity. The methanol extract and other three fractions exhibited better activities at higher concentrations. Bacillus megaterium and Klebsiella spp.
Background: Caesalpinia bonducella L. It is a prickly shrub widely distributed all over the world especially in Indian tropical regions such as Kerala, Andaman and Nicobar Islands and Sri Lanka. Materials and Methods: The aqueous extract of Caesalpinia bonducella nut containing the seed and the shell, has been evaluated for qualitative analysis of secondary metabolites tannis, flavonoids, alkaloids, saponins, coumarins, quinone and phenols , in-vitro anti -inflammatory, anti-diabetic assay, antioxidant, antimitotic and antimicrobial activity. The studies were carried out using HRBC membrane stabilization, inhibition of alpha amalyse enzyme, DPPH method, green gram growth inhibition, agar diffusion method respectively. Results: Our results indicate the presence of Alkaloids, Flavanoids and Saponins. We report in our study the antidiabetic, anti-inflammatory, anti-oxidant, anti-microbial and antimitotic activity of Caesalpinia bonducella. Wholesale Shoes Online.