LITHOGENESIS AND BILE METABOLISM PDF

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Gallstone disease exacts a considerable financial and social burden worldwide leading to frequent physician visits and hospitalizations. Based on their composition, gallstones are categorized as cholesterol, black pigment, and brown pigment, with each category having a unique structural, epidemiologic, and risk factor profile.

Some risk factors for cholesterol stones include age, gender, genetics, obesity, rapid weight loss, and ileal disease. Generally, pigment stones are formed by the precipitation of bilirubin in bile, with black stones associated with chronic hemolytic states, cirrhosis, Gilbert syndrome, or cystic fibrosis, and brown stones associated with chronic bacterial or parasitic infections.

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Full-text links Cite Favorites. Abstract Gallstone disease exacts a considerable financial and social burden worldwide leading to frequent physician visits and hospitalizations. Similar articles Pathogenesis of gallstones. Carey MC. Recenti Prog Med. PMID: Review. Pigment gallstone disease. Trotman BW. Gastroenterol Clin North Am. Pathophysiological preconditions promoting mixed "black" pigment plus cholesterol gallstones in a DeltaF mouse model of cystic fibrosis. Freudenberg F, et al. Epub Apr Solubility of cholesterol in the crystal-free gallbladder bile of gallstone patients.

J Lab Clin Med. PMID: Cas Lek Cesk. Show more similar articles See all similar articles. Cited by 15 articles Ectopic papilla of Vater in duodenum bulb: A hospital-based study.

Peng YC, et al. Medicine Baltimore. Clinical Trial. Bale G, et al. J Clin Exp Hepatol. Epub Dec Spontaneously removed biliary stent drainage versus T-tube drainage after laparoscopic common bile duct exploration. Xu Y, et al. Association between gallbladder stone disease and prostate cancer: A nationwide population-based study.

Chen CH, et al. Prevalence of and risk factors for gallstones in Uighur and Han Chinese. Zhu L, et al. World J Gastroenterol. Show more "Cited by" articles See all "Cited by" articles. Publication types Review Actions. Humans Actions. Risk Factors Actions. Substances Bile Acids and Salts Actions. Full-text links [x] Elsevier Science. Copy Download.

CONFESSIONS OF AN INTERGALACTIC ANTHROPOLOGIST PDF

Lithogenesis and Bile Metabolism

Gallstone disease exacts a considerable financial and social burden worldwide leading to frequent physician visits and hospitalizations. Based on their composition, gallstones are categorized as cholesterol, black pigment, and brown pigment, with each category having a unique structural, epidemiologic, and risk factor profile. Some risk factors for cholesterol stones include age, gender, genetics, obesity, rapid weight loss, and ileal disease. Generally, pigment stones are formed by the precipitation of bilirubin in bile, with black stones associated with chronic hemolytic states, cirrhosis, Gilbert syndrome, or cystic fibrosis, and brown stones associated with chronic bacterial or parasitic infections. This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable.

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Bile Metabolism and Lithogenesis: An Update

Kathleen O'Connell, Karen Brasel. Our understanding of bile metabolism and the molecular effects of bile acids has expanded in recent years. Bile acids, which are classically recognized for their involvement in dietary lipid absorption, are now known to be involved in many aspects of energy metabolism and disease processes in humans. Cholelithiasis, a consequence of altered bile metabolism, affects a significant number of American adults. An understanding of the disease process, risk factors, and complications of gallbladder disease is necessary for the development of novel targeted treatments and prophylactic therapies against the development of gallstones. Bile metabolism and lithogenesis.

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Bile Metabolism and Lithogenesis: An Update.

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