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In these systems, drugs are described either in Sanskrit or vernacular languages. Avartani Helicteres isora Linn. It is commonly known as Marodphali, Marorphali, Enthani etc. Avartani is used as a folk medicine to treat snake bite, diarrhoea and constipation of new born baby. In the research, antioxidant, hypolipidaemic, antibacterial and antiplasmid activities, cardiac antioxidant, antiperoxidative potency, brain-antioxidation potency, anticancer activity, antinociceptive activity, hepatoprotective activity, anti-diarrheal activity and wormicidal activity in this plant were reviewed.
The definition of Helicteres is a large genus of tropical trees and shrubs family Sterculiaceae with axillary flowers and fruits consisting of five twisted carpels. The origin of Helicteres is NL, fr. Isora is a Japanese name for boys meaning God of the seashore . Avartani [ Helicteres isora Linn. It is not described broadly in old text of Ayurveda, i.
Samhitas and Nighantu. This plant maybe comes from outside so that it is neglected by Ayurvedic authors. In the description of the Ayurvedic plant Murva, Avartani is also confused with Murva, but later it is confirmed with a separate plant rather than Murva Marsdenia tenacissima W. The leaf of Avartani shows similarity with Parushaka Grewia asiatica Linn. The botanical name of Avartani is H. The scientific classification of Avartani H. It is sub-deciduous small tree or shrub of about 1.
Young branches are rough with scattered stellate hairs. The leaves are serrate, obliquely cordate or ovate, shortly acuminate and rough above and pubescent beneath.
The flowers are solitary or in sparse clusters with red reflexed petals, become pale-blue when old. The fruits are 5. The seeds are tubercled.
Fruits, seeds, bark and roots of the plant are used. The flowering time of H. The Ayurvedic guna properties are given in Table 3. Ayurvedic karma are atisaraghna anti-diarrheal , sula-prashmana analgesic , krimighna wormicidal , rakta-shodhaka blood purifier , Mutra-sangrahniya urine conservative . In Konkan, the fruits are used as a remedy for snake bite.
The fruits are used in diarrhoea as well as constipation of new born baby . In the aqueous extract of its root, one teaspoonful tid is given for d for the treatment of dog-bite in Utter Pradesh . Tribals of Singbhum district of Bihar use the fruits as an amulet in neck to treat disease of malnutrition, which is locally known as Dubli disease among children . Satake et al. The structures of these compounds, including the absolute stereochemistry of 4 , were elucidated by spectroscopic analysis and chemical means.
Compound 3 had greater scavenging activity against superoxide anion produced with xanthine and xanthine oxidase than rosmarinic acid 1 . Ramesh et al. Saraswatiibhai led to the identification of choloplast, pigments, phytosterols, hydroxyl carboxylic acid, orange-yellow colouring matter, saponins, phlobotannis, sugar ang lignins .
A preliminary study of phytoconstituents of seeds by Nair and Grampurohit showed the presence of phytosterols, fixed oils and fats, phenolic compounds and tannins and amino acid and carbohydrates . Cucurbitacin B and isocucurbitacin B have been isolated from its root .
Kumar et al. Dot plot assay confirmed the presence of antioxidant activity. Acetone fruit extract of H. Acetone extract exhibited better cytotoxicity against human lung cancer cells NCI-H ; whereas acetone and crude protein extracts showed activity against reactive oxygen species.
The investigation revealed the antioxidant and anticancer activity of H. The effect of bark extracts of H. The treatment with H. But the treatment of H. The treatment of bark extract reversed the increased levels of these lipid ratios and normalized soon after . Boopathy Raja et al. Shriram et al. These finding resulted in the possibility of a new type of combination between antibiotics and potential drugs effective against plasmid encoded multiple antibiotic resistance.
The concentrations of the curing agents used in this study were sub inhibitory, since bacteria were already resistant to these concentrations of compound. It can be assumed that bacteria are less likely to develop any mechanism to counter the plasmid curing property of the acetone extract of H.
They presented significant increases in the diabetic rats treated with hemagglutination inhibition HI. Administration of HI to normal rats increased the antioxidant levels with no other significant differences. The effect produced by HI was comparable with that of tolbutamide. The above observation shows that the aqueous extract of bark of H. Varghese et al. The cytotoxic activity of the drug is due to the presence of alkaloids and flavonoids. Our further plan is to isolate and evaluate these active principles and elucidate exact mechanism of action.
Venkatesh et al. Phytochemical analysis of the active extracts indicated that their major constituents are sterol, triterpenoids petroleum ether extract , and their glycosides chloroform and aqueous ethanol extracts may be responsible for observed pharmacological activity . Chitra et al. The parameters studied were serum total bilirubin, total protein, alanine transaminase, aspartate transaminase and alkaline phosphatase activities.
Results of biochemical studies of blood samples of CCl 4 treated animals showed significant increase in the levels of serum markers and decrease in total protein level reflecting the liver injury caused by CCl 4 . The fruits are demulcent and astringent and are useful in the gripping of bowels and flatulence of children. The bark is useful in dysentery and diarrhoea . The pods are fried and given to children to kill intestinal worms .
Numerous studies have been conducted on different parts of Avartani H. A detailed and systematic study is required for identification, cataloguing and documentation of plants, which may provide a meaningful way for promoting traditional knowledge of the medicinal herbal plant. The author is thankful with core of heart to Dr.
Joshi V. Diwedi K. Shivani Ghildiyal, Dr. Anjali and Dr. Kanhaiya for valuable guidance. This is a review article pertaining to well known medicinal plant - H. It is a need of present era to search remedies of common disorders by natural products. The present article makes acquainted with medicinal properties and useful therapeutic indications of the medicinal plant H. It is better to encourage the use of this naturally occurring plant and its parts in place of synthetic drugs.
Several studies have been carried out regarding its use in varios disorders, and they are quoted by the authors in reference at the end of the article which support its rational use in those disorders.
Authors have highlighted its therapeutic uses in today's context. The review descirbed the use of H. This is a good review done on H. This is further supported by planned research works carried out by different research workers of its antioxidant, hypolipidaemic, cardio protective, anti peroxidative, antibacterial, anti cancer, anti nociceptive, hepatoprotective etc.
Conflict of interest statement: We declare that we have no conflict of interest. National Center for Biotechnology Information , U. Asian Pac J Trop Biomed. Reviewed by Prof. Author information Article notes Copyright and License information Disclaimer. Comments This is a good review done on H.
Details on Page S Received Jan 20; Accepted Mar 2. All rights reserved. This article has been cited by other articles in PMC. Keywords: Avartani, Ayurveda, Helicteres isora Linn. Introduction The definition of Helicteres is a large genus of tropical trees and shrubs family Sterculiaceae with axillary flowers and fruits consisting of five twisted carpels. Avartani H. Table 1 Name of Avartani in different languages.
Open in a separate window. Table 2 Scientific classification of Avartani.
A beaked, spirally twisted follicle, stellate tomentose; seeds numerous, wrinkled, truncate. Fruiting from December-March. Best supported on Google Chrome, Firefox 3. Powered by the open source Biodiversity Informatics Platform. Technology partner Strand Life Sciences. India Biodiversity Portal.
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Helicteres isora L. It is occasionally grown in Java. In India it is known as "kaivun fibre" and is used for making ropes and sacks and as supplementary raw material for paper making. In Indonesia, Malaysia, Thailand and India the fruit known in the Javanese medicine trade as " buah kayu ules", "kayu puter" or "ulet-ulet" is used internally or externally against intestinal complaints, particularly in children. In Malaysia and southern Thailand the dried fruit is employed in compound tonics, especially those given after childbirth. In India H.
Helicteres isora L.
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