We'd like to understand how you use our websites in order to improve them. Register your interest. La mayor parte de estas aread correspondieron a la heterocromatina constitutiva. Se sugiere que estas regiones corresponden al a heterocromatina facultative.

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Heterochromatin decondesation in Creole cattle carrier of Robertsonian franslocation rob 1; Action of 5-azacytidine-C. Facultad de Veterinaria. Lasplaces Fax: Montevideo, Uruguay.

Autor para correspondencia: aliposvet gmail. The Robertsonian translocation rob1; 29 is widely spread in commercial breeds and specially in genetic reserve of American Creole cattle. It is also described a delay on embryo development in front of normal ones. The action of 5-aza-C, as an hypomethylated agent, could permitted to decondensate the constitutive or facultative heterochromatin. In this work we made induction with the 5-aza-C 10mM, 2 hrs analogs, in lymphocyte cultures of female and male carriers and normal Creole cattle.

The DNA hypometilation is found in the inactive X chromosome of late replication as it is incorporated during the last hours of cell culture.

The decondensing effects of 5-aza-C analogs is observed in multiple regions of the autosomes chromatin, the rob1; 29 and the BTA1. A correlation between hypometilated regions and decondensed of facultative conditional heterochromatin is related with genomic instability, and epigenetic reprogramming.

Di Meo y col. Tellechea y col. El colcemid 0. Se observaron regiones condensadas que no fueron alteradas por el inductor. Arruga, M. Artigas, R. Danielak-Czech, B ; Slota, E.. Mutagen-induced chromosome instability in farm animals.

J Anim Feed Sci De Luca, JC. Theriogenology 15; 58 7 : Di Berardino, D. Localization of BrdU-induced break sites in bovine chromosomes. Caryologia 36 3 Cytogenet Cell Genet Di Meo, A. Chromosome Res Gustavsson, I. Cytogenetics, distribution and phenotypic effects of a translocation in Swedish cattle. Hereditas Haaf, T. The effects of 5-azacytidine and 5-azadeoxicytidine on chromosome structure and function: implications for methylation- associated cellular process.

Thr Experimental condensation inhibition in constitutive heterochromatin of mammalian chromosomes. Cell Genet Holmquist, G. Chromosome organization and chromatin modification: influence on genome function and evolution. Joerg, H. J Anim Breed Genet Kastelic, JK. Causas no infecciosas de muerte embrionaria en ganado bovino. King, WA. Embryo-mediated pregnancy failure in cattle.

Can Vet J Pintado, E. Rev Neurol , Postiglioni, A. Cytogenetic Characterization of a sample of Uruguayan Creole cattle. Arch Zootec Rangel-Figueiredo, T. Frequency and distribution of rob 1; 29 in three Portuguese cattle breeds. Rev Col Cienc Pec Schifferli, C. Shibler, L. Genome Res Sumner, A. A simple technique for demonstrating centromeric heterochromatin. Tellechea, B.

Avances en el estudio de la heterocromatina en rob1; Wurster, DH. Services on Demand Article. Spanish pdf Article in xml format Article references How to cite this article Automatic translation Send this article by e-mail. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Cra 32 no. How to cite this article.


Departamento de Biología y Química

A new species of Urostreptus Diplopoda, Spirostreptidae : description and chromossome number. This work presents the description and chromosome number of Urostreptus atrobrunneus sp. The C-banding revealed large blocks of constitutive heterochromatin and two heteromorphic chromosomal pairs, one of them corresponding to the sexual pair. Keywords: Urostreptus , Diplopoda, cytogenetics, banding. Urostreptus Silvestri, belongs to Spirostreptidae, being distributed throughout South America and characterized for presenting a median prominent carina on the epiproctum. These animals have an average size and a thin body. Six species of Urostreptus have been reported in Brazil, with their distribution concentrated at the central States and, according to HOFFMAN , their absence at the eastern and southeastern parts of the country is noteworthy.


Constitutive heterochromatin formation and transcription in mammals. For all author emails, please log on. Constitutive heterochromatin, mainly formed at the gene-poor regions of pericentromeres, is believed to ensure a condensed and transcriptionally inert chromatin conformation. Pericentromeres consist of repetitive tandem satellite repeats and are crucial chromosomal elements that are responsible for accurate chromosome segregation in mitosis. The repeat sequences are not conserved and can greatly vary between different organisms, suggesting that pericentromeric functions might be controlled epigenetically. In this review, we will discuss how constitutive heterochromatin is formed and maintained at pericentromeres in order to ensure their integrity. We will describe the biogenesis and the function of main epigenetic pathways that are involved and how they are interconnected.

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