CAYRATIA TRIFOLIA PDF

Cayratia trifolia Linn. Domin Syn. It is native to India, Asia and Australia. It is a perennial climber having trifoliated leaves with cm long petioles and ovate to oblong-ovate leaflets.

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Cayratia trifolia Linn. Domin Syn. It is native to India, Asia and Australia. It is a perennial climber having trifoliated leaves with cm long petioles and ovate to oblong-ovate leaflets. Flowers are small greenish white and brown in color.

Fruits are fleshy, juicy, dark purple or black, nearly spherical, about 1 cm in diameter. It is found throughout the hills in India. This perennial climber is also found in the hotter part of India from Jammu and Rajasthan to Assam extending into the peninusular India upto m height. Leaves contain stilbenes piceid, reveratrol, viniferin, ampelopsin. Stem, leaves, roots are reported to possess hydrocyanic acid, delphinidin and several flavonoids such as cyanidin is reported in the leaves.

This plant also contains kaempferol, myricetin, quercetin, triterpenes and epifriedelanol. Infusion of seeds along with extract of tubers is traditionally given orally to diabetic patients to check sugar level of blood.

Paste of tuberous is applied on the affected part in the treatment of snake bite. Whole plant is used as diuretic, in tumors, neuralgia and splenopathy. Its climbers wrapped around the neck of frantic bullock and poultice of leaves are used to yoke sores of bullock. The bark extract shows the antiviral, antibacterial, antiprotozoal, hypoglycemic, anticancer and diuretic activity.

This article focuses on the upgraded review on chemical and biological properties of Cayratia trifolia Linn. Domin syn. Vitis trifolia Linn. Family:Vitaceae is a native of India, Asia and Australia. Cayratia trifolia is also known by various synonyms[ 7 — 11 ] such as:. Different vernacular names[ 6 ] of Cayratia trifolia have been reported in Table 1. The taxonomical hierarchy[ 4 , 13 ] of Cayratia trifolia has been mentioned in Table 2. Cayratia trifolia is a weak herbaceous climber, woody at base, stem is more or less succulent, compressed and densely.

Leaves are trifoliolate with petioles cm long. Leaflets are ovate to oblong-ovate, cm long, 1. Flowers are small greenish white 2. Seeds are triangular, apex rounded, ventral holes and ribs obtuse along margin, slightly raised. Cayratia trifolia is known as kalit--kalit in Philippines where it is found at low altitudes. It also found throughout the hilly regions in India. Several flavonoids such as cyanidin are reported in the leaves.

Fruits also contain calcium oxalate responsible for severe irritation in the mouth. Whole plant is used as diuretic and is also useful in tumors, neuralgia and splenopathy, leucorrhea,[ 6 , 16 ] astringent. Sap of stems and juice of leaves are used as aphrodisiac. Roots are grounded with black peeper and applied as poultice on boils. The bark extract showed The plant is reported to have antibacterial, antifungal, antiprotozoal, hypoglycemic, anticancer and diuretic actions.

Poultice of leaves are used for yoke sores of bullock and also used to cure swelling, injury and infection. Fruits are edible, pleasantly acidic in taste. The powdered plants were continuously extracted with petroleum ether, chloroform, ethyl acetate and methanol. The crude extract of ethyl acetate and methanol were tested for their biological activity including antioxidant activity by scavenging effect on DPPH 1,1-diphenylpicryl hydraryl radicals.

The crude extract of Cayratia trifolia showed the ED 50 values of Crude extract of this plant was tested in preliminary biological screening for their antimicrobial activity against Escherichia coli , Bacillus subtilis , Micrococcus luteus and P.

Precleaned extract was also investigated for their ability to inhibit protein kinase and tyrosine-specific protein kinase of epidermal growth factor.

A large variety of phytochemical constituents that have been reported from natural product research has been proven successfully as anticancerous agent. The finding from the study reveals that methanolic extract is more potent than aqueous extract in exerting antineoplastic effect in both cell lines as evident by a dose dependent decrease in cell growth. Delphidin and cyaniding which are anthocyanin and showed antiproliferative and proapoptotic properties in gastric adenocarcinoma and were also found to be protective against esophageal cancer in rodents.

The dietary supplementation with resveratrol significantly reduced plaque formation in animal brains, a component of Alzheimer and other neurodegenerative disease. In a rat model of carrageenan-induced Paw edema, resveratrol inhibited both acute and chronic phases of the anti-inflammatory process.

It inhibits the vascular cell adhesion molecular expression. Inhibition of vascular smooth muscle cell proliferation[ 47 — 49 ]. Stimulation of endolethelial nitric oxide synthase activity[ 50 — 52 ].

Inhibition of platelet aggregation[ 53 — 55 ]. It possesses hypoglycemic and hypolipidemic effect in both Streptozotacin-induced diabetes rats and STZ-Nicotinamide-induced diabetes rats. Other diabetic animal model studies by different researches have also demonstrated the antidiabetic effect of resveratrol. It inhibits herpes simplex virus types 1 and 2 replication by inhibition of an early step in virus replication cycle.

In vivo studies in mice shows that resveratrol inhibits or reduce HSV replication in the vagina and limits extra-vaginal disease. This paper provides valuable information about plant. Such information may serve as a base for new pharmacognostical, phytochemical, pharmacological, toxicological and clinical research. Conflict of Interest: None declared. National Center for Biotechnology Information , U.

Journal List Pharmacogn Rev v. Pharmacogn Rev. Ankit Gupta 1 G. Author information Article notes Copyright and License information Disclaimer.

Address for correspondence: Dr. E-mail: ni. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.

This article has been cited by other articles in PMC. Abstract Cayratia trifolia Linn. Keywords: Biological, Cayratia trifolia , chemical, review. Cissus carnosa Lamk. Vitis carnosa Lamk. Lawson Cissus trifolia Linn. Schaum Cayratia carnosa Lamk. Local names Different vernacular names[ 6 ] of Cayratia trifolia have been reported in Table 1. Table 1 Vernacular names of Cayratia trifolia. Open in a separate window.

Taxonomical hierarchy The taxonomical hierarchy[ 4 , 13 ] of Cayratia trifolia has been mentioned in Table 2. Table 2 Taxonomical hierarchy of Cayratia trifolia. Botanical distribution Cayratia trifolia is a weak herbaceous climber, woody at base, stem is more or less succulent, compressed and densely.

Figure 1. Geographical distribution Cayratia trifolia is known as kalit--kalit in Philippines where it is found at low altitudes. Chemical constituents This plant also contains kaempferol, myricetin, quercetin, triterpenes and epifriedelanol. Ethnomedicinal uses Whole plant is used as diuretic and is also useful in tumors, neuralgia and splenopathy, leucorrhea,[ 6 , 16 ] astringent.

Veterinary uses Poultice of leaves are used for yoke sores of bullock and also used to cure swelling, injury and infection. Non-medicinal uses Fruits are edible, pleasantly acidic in taste.

Antimicrobial activity Crude extract of this plant was tested in preliminary biological screening for their antimicrobial activity against Escherichia coli , Bacillus subtilis , Micrococcus luteus and P. Anticancer activity A large variety of phytochemical constituents that have been reported from natural product research has been proven successfully as anticancerous agent. Neuroprotective effect The dietary supplementation with resveratrol significantly reduced plaque formation in animal brains, a component of Alzheimer and other neurodegenerative disease.

Anti-inflammatory effect In a rat model of carrageenan-induced Paw edema, resveratrol inhibited both acute and chronic phases of the anti-inflammatory process. Cardioprotective effects It inhibits the vascular cell adhesion molecular expression. Antidiabetic effect It possesses hypoglycemic and hypolipidemic effect in both Streptozotacin-induced diabetes rats and STZ-Nicotinamide-induced diabetes rats.

Antiviral effect It inhibits herpes simplex virus types 1 and 2 replication by inhibition of an early step in virus replication cycle. Lewington A. Cambridge, UK: Traffic International; Medicinal plants and plant Extracts: A review of their importation into Europe. Maurya R, Gupta CM.

Traditional herbs for modern medicine.

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Cayratia trifolia (L.) Domin medicinal uses

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Cayratia trifolia L. Vitis trifolia L. In Peninsular Malaysia, the leaves and roots are commonly used for poulticing ulcers of the nose. A decoction of the leaves and roots or the fresh juice of the leaves and stem are also used for high fever. In Java, the juice of the leaves, together with the juice of young pineapple is used on the head for itch and dandruff.

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